campsisnca: Non-Compartmental Analysis for Campsis Simulation Platform
A flexible and user-friendly non-compartmental analysis (NCA)
toolkit designed to work seamlessly with simulated pharmacokinetic
data generated using the 'campsis' ecosystem. The package provides a
comprehensive framework to compute standard and custom NCA metrics,
including exposure (AUC), peak/trough concentrations, half-life and
time-above/below thresholds, with support for configurable time
windows and summary statistics. 'campsisnca' integrates tightly with
'campsis' and 'campsismod', enabling streamlined workflows from
simulation to analysis. In addition, the package provides a JSON-based
interface to define NCA analyses, metrics and options using formal
schemas, allowing analyses to be created, validated and executed
outside of R and facilitating reproducibility, automation and system
integration. The package also includes utilities for generating
formatted summary tables and exporting results in multiple formats
suitable for reporting. Trapezoidal rule implementation for AUC
calculation is based on the 'qpNCA' package by Huisman, Jolling,
Mehta and Bergsma (2021) <doi:10.32614/CRAN.package.qpNCA>,
following methodology from Rowland and Tozer (2011,
ISBN:978-0-683-07404-8). The package itself is licensed under the
GPL (>= 3); the JSON schema files shipped in inst/extdata are
licensed separately under the Creative Commons Attribution 4.0
International (CC BY 4.0).
| Version: |
1.7.1 |
| Depends: |
campsismod, R (≥ 4.0.0) |
| Imports: |
assertthat, campsis, cards, dplyr, glue, gt, gtsummary, jsonlite, jsonvalidate, lifecycle, magrittr, methods, purrr, rlang, stringr, tibble, tidyr |
| Suggests: |
devtools, ggplot2, mrgsolve, pkgdown, rmarkdown, roxygen2, rxode2, testthat |
| Published: |
2026-09-15 |
| DOI: |
10.32614/CRAN.package.campsisnca (may not be active yet) |
| Author: |
Nicolas Luyckx [aut, cre] |
| Maintainer: |
Nicolas Luyckx <nicolas.luyckx at calvagone.com> |
| BugReports: |
https://github.com/Calvagone/campsisnca/issues |
| License: |
GPL (≥ 3) |
| URL: |
https://github.com/Calvagone/campsisnca |
| NeedsCompilation: |
no |
| Language: |
en-US |
| Materials: |
README, NEWS |
| CRAN checks: |
campsisnca results |
Documentation:
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