SPACO: Spatial Component Analysis for Spatial Sequencing Data

Spatial components offer tools for dimension reduction and spatially variable gene detection for high dimensional spatial transcriptomics data. Construction of a projection onto low-dimensional feature space of spatially dependent metagenes offers pre-processing to clustering, testing for spatial variability and denoising of spatial expression patterns. For more details, see Koehler et al. (2026) <doi:10.1093/bioinformatics/btag052>.

Version: 1.0.0
Depends: R (≥ 4.2.3)
Imports: ggplot2, Seurat (≥ 5.3.0), tibble, ggforce, methods, rARPACK, tidyr, mgcv, scales, Matrix (≥ 1.5)
LinkingTo: Rcpp, RcppEigen
Suggests: testthat (≥ 3.0.0)
Published: 2026-03-31
DOI: 10.32614/CRAN.package.SPACO (may not be active yet)
Author: David Köhler ORCID iD [aut, cre]
Maintainer: David Köhler <koehler at imbie.uni-bonn.de>
License: MIT + file LICENSE
NeedsCompilation: yes
CRAN checks: SPACO results [issues need fixing before 2026-04-14]

Documentation:

Reference manual: SPACO.html , SPACO.pdf

Downloads:

Package source: SPACO_1.0.0.tar.gz
Windows binaries: r-devel: not available, r-release: not available, r-oldrel: not available
macOS binaries: r-release (arm64): SPACO_1.0.0.tgz, r-oldrel (arm64): not available, r-release (x86_64): SPACO_1.0.0.tgz, r-oldrel (x86_64): SPACO_1.0.0.tgz

Linking:

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